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Dr. O’Mahony is founder of Neural Education, the Institute for Connecting Neuroscience with Teaching and Learning, an educational non-profit in the State of Washington that facilitates teacher Professional Development for twenty-first century learners. As Co-PI on the National Institutes for Health (NIH) five-year research program (How Do I Learn), Dr. O’Mahony formulated an educational methodology centered on the human brain, which optimizes, through a brain-based pedagogic model, all children’s potential. This work situated at the intersection of pedagogy, learning sciences, and neuroscience is a practical collaboration that explicates relevant neuro-knowledge, which profoundly impacts learning and human potential. This work is accomplished through incorporating theories of action and methods that align neuroscience with how the human brain works and how children learn, within existing systems and within a framework of adaptive expertise.